Publications
2021
- Huynh, A. and Wood, K. Antibiotic Resistance: Finding the Right Sequence of Drugs [Insight Article], eLife, doi: 10.7554/eLife.72562 (2021).
- Gjini, E. and Wood, K. Price equation captures the role of drug interactions and collateral effects in the evolution of multidrug resistance, eLife, doi: 10.7554:e64851 (2021).
Part of eLife's Special Issue on Evolutionary Medicine.
- Sharma, A. and Wood, K. Spatial segregation and cooperation in radially expanding microbial colonies under antibiotic stress, ISME, doi: 10.1038/s41396-021-00982-2 (2021).
- Wood, K. Time-dependent drug sequences for slowing antibiotic resistance. In Roadmap on biology in time varying environments (Murugan et al), Physical Biology (2021).
2020
- Maltas, J., McNally, D., and Wood, K. Evolution in alternating environments with tunable inter-landscape correlations, Evolution, 75 (1), 10-24 (2020).
- Hansen**, E., Karslake**, J., Woods, R.J., Read, A.F., and Wood, K. Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations, PLOS Biology, 18 (5), e3000713 (2020).
- Hallinen, K., Guardiola-Flores, K. A., and Wood, K. Fluorescent reporter plasmids for single-cell and bulk-level composition assays in E. faecalis, PLOS One, 15(5): e0232539 (2020).
- Hallinen**, K., Karslake**,J. , and Wood, K. Delayed antibiotic exposure induces population collapse in enterococcal communities with drug-resistant subpopulations, eLife, doi: 10.7554/eLife.52813 (2020). eLife Digest
- Dean, Z., Maltas, J., and Wood, K. Antibiotic interactions shape short-term evolution of resistance in E. faecalis, PLOS Pathogens, 16(3): e1008278 (2020).
2019
- Maltas, J., Krasnick, B., and Wood, K. Using selection by non-antibiotic stressors to sensitize bacteria to antibiotics, Molecular Biology and Evolution, doi:10.1093/molbev/msz303 (2019).
- Maltas, J., and Wood, K. Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance, PLOS Biology 17(10), e300515, 2019.
- Wood, K. Microbial Ecology: Complex Bacterial Communities Reduce Selection for Antibiotic Resistance [Invited Dispatch], Current Biology, 29, R1143-1145, 2019.
2018
- De Jong, M. G., and Wood, K. Tuning spatial profiles of selection pressure to modulate the evolution of drug resistance, Physical Review Letters, 120 (23), 2018. PDF
- Yu, W., Hallinen, K., and Wood, K., Interplay between antibiotic efficacy and drug-induced lysis underlies enhanced biofilm formation at subinhibitory drug concentrations, Antimicrobial Agents and Chemotherapy, 62 (1), 2018.
Pre-2018
- Karslake, J., Maltas, J., Brumm, P., and Wood, K., Population density modulates drug inhibition and gives rise to potential bistability of treatment outcomes for bacterial infections, PLOS Computational Biology 12 (10) (2016).
- Wood, K. Pairwise interactions and the battle against combinatorics in multidrug therapies [Invited Commentary], P Natl Acad Sci USA (2016).
- Yu, W. and Wood, K., Synchronization and phase redistribution in self-replicating populations of coupled oscillators and excitable elements, Phys. Rev. E, 91, 062708 (2015).
Published (previous work, drug interactions)
- Wood, K., Wood, K.C., Nishida, S., Cluzel, P. Uncovering scaling laws to infer multi-drug response of resistant microbes and cancer cells. Cell Reports 6, 1073 (2014).
- Wood, K., Nishida, S., Sontag, E.D. & Cluzel, P. Mechanism-independent method for predicting response to multidrug combinations in bacteria. P Natl Acad Sci USA 109, 12254-12259 (2012).
- Wood, K. & Cluzel, P. Trade-offs between drug toxicity and benefit in the multi-antibiotic resistance system underlie optimal growth of E. coli. BMC Syst Biol 6, 48 (2012).
Published (previous work, nonequilibrium physics)
- Wood, K., Van den Broeck C., Kawai R., Lindenberg, K., Continuous and discontinuous phase transitions and partial synchronization in stochastic three-state oscillators, Phys. Rev. E, 76, 041132, 2007.
- Cao, F., Wood, K., Lindenberg, K. Noise-induced phase transitions in field-dependent relaxational dynamics: The Gaussian ansatz, Phys. Rev. E, 76, 051111, 2007.
- Wood, K., Van den Broeck C., Kawai R., Lindenberg, K., Fluctuation Theorem for the Eff usion of an Ideal Gas with Momentum Transfer, Phys. Rev. E, 75, 061116, 2007.
- Wood, K., Van den Broeck C., Kawai R., Lindenberg, K., Eff ects of Disorder on Synchronization of Discrete Phase-Coupled Oscillators, Phys. Rev. E, 75, 041107, 2007.
- Wood, K., Van den Broeck C., Kawai R., and Lindenberg, K., Synchrony and critical behavior: Equilibrium universality in nonequilibrium stochastic oscillators, AIP Proc. 913, 49, 2007.
- Wood, K., Van den Broeck C., Kawai R., Lindenberg, K., Critical Behavior and Synchronization of Discrete Stochastic Phase Coupled Oscillators, Phys. Rev. E, 74, 031113, 2006.
- Wood, K., Van den Broeck C., Kawai R., Lindenberg, K., The Universality of Synchrony: Critical Behavior in a Discrete Model of Stochastic Phase Coupled Oscillators, Phys. Rev.Lett., 96, 145701, 2006.
- Buceta, J., Wood, K., Lindenberg, K. , Noise-induced oscillatory behavior in field-dependent relaxational dynamics, Phys. Rev. E, 73, 042101, 2006.
- Wood, K., Buceta, J., Lindenberg, K., Comprehensive Study of Pattern Formation in Relaxational Systems, Phys. Rev. E, 73, 022101, 2006.